Impact after 3 years of application of enteral paromomycin to eradicate colistin and carbepemenase resistant microrganisms in rectal colonization to prevent ICU infections
نویسندگان
چکیده
Introduction Emergence of carbapemenases and their worldwide distribution has worsens the clinical scenario of antibiotic resistance in Gram-negative bacteria. Selective Digestive Decontamination (SDD) has been used to prevent development of nosocomial colonization and infections in ICU patients. However, rectal colonization with multirresistant bacteria is a serious concern with SDD. An effective enteral antimicrobial treatment in this scenario is still lacking and it might contribute to prevent systemic nosocomial infections.
منابع مشابه
Three years application of selective digestive decontamination in a mixed intensive care unit in a university hospital: impact on colonization, infection and antibiotic consumption
Methods This study was conducted in a 30-bed-medical-surgical ICU. All consecutive patients admitted to the from October 1, 2011 to September 30, 2014 expected to require tracheal intubation for longer than 48 hours were given SDD (SDD study group) with a 4-day course of intravenous cefotaxime, plus enteral colistin, tobramycin, nystatin in an oropharyngeal paste and in a digestive solution. Or...
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